Work experience

Cytiva (a part of Danaher)

Led operational procedure development and authored SOPs for GMP manufacturing, ensuring process quality and compliance.
Executed and planned various client batches requiring process development to large-scale manufacturing from early proof-of-concept studies.
Participated in Kaizen events, enhancing the drug development process, and contributing to the knowledge base required for LNP formulation improvements.
Indirectly managed and mentored junior team members, providing guidance and support to help them develop professionally and personally.
Collaborated and executed clinical production batches, liaising with clients for technical process support from pre-clinical to clinical stages.

Interacted with customers and clients to understand their manufacturing needs and provided technical support for process development of formulations from pre-clinical to clinical stage.
Inspired and influenced team members through strategic guidance, fostering an environment that encourages continuous learning and innovation within the team.
Optimized downstream processing using centrifugal filtration and dialysis for small-scale batches and Tangential Flow Filtration (TFF) for large-scale batches.
Prepared engineering and GLP-tox batches for client projects and led projects to the clinical manufacturing process.
Led and managed to simultaneously work on multiple client projects from planning and performing experiments to presenting and discussing data with the client.
Supported tech transfers, essential for transferring processes to clients for final batch preparation.

Process development and scale-up of formulations including working on technology transfer projects.
Optimization of downstream processing using Tangential Flow Filtration.
Working on optimization of process parameters for lyophilization of RNA LNPs.
Led and managed projects being a point of contact for various clients simultaneously.
Creating workflows to achieve standardization of protocols.

Prepared formulations of lipid nanoparticles and polymeric nanoparticles for nucleic acid delivery using PNI NanoAssemblr.
Conducted thorough literature research to develop formulations using NanoAssemblr microfluidic devices based on client needs.
Led extensive research activities on the process conditions and effects of lyophilizer on LNP size and EE% of payloads.
Designed experiments using DOEs using Design-Expert software to optimize the primary drying step in the lyophilization of lipid nanoparticles.
Optimized tangential flow filtration parameters and studied process parameters to reduce the operating time for downstream processing.
Worked together as a team to achieve excellence with engineering, manufacturing, and scientists to help the pharmaceutical industry in drug discovery and development.
Designed prototypes for lab equipment and materials using 3D SolidWorks.
Performed experimental mixture design using Design Expert to optimize in-vitro potency of various lipid mix concentrations and achieved a 10-fold increase in potency compared to control formulation leading to three different patents.
Prepare Standard Operating Procedures (SOPs), batch cGMP reports, review SOWs, and technical presentations.